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No one knows what exactly causes fibromyalgia. Some possible triggers can include:

Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people who go through it you ought to err assisting caution and let the FDA do its job and demand some research be done so your public recognizes the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say everything to keep people on their own medications.

Researchers found out that participants taking this drug to get a year, lost excess weight within one month and have kept the extra weight off throughout the 56 weeks of the study. Contrave is really a combination of the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, which may make them more effective and safer.

Combo-pilling may be the newest fad or also the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular may be the fact that at the time of right now there aren't any long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug also can raise blood pressure and heart rate, and shouldn't be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients for the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.


"This will be the first drug I'm aware of that targets both appetite and reward centres in the brain," he said.

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